Вакцина SARS-CoV-2 inactivated vaccine
Международное непатентованное наименование
Вакцина SARS-CoV-2 inactivated vaccine
Торговое наименование
-
Производитель, страна
Sinovac Research and Development Co., China
Механизм действия
Inactive viral vaccines are created by propagating viruses in cell culture (such as in Vero cells) followed by inactivation using a chemical reagent (such as beta-propiolactone). Upon vaccination, this allows the body to generate a diverse immune response against numerous viral antigens while having no threat of actually being infected because the virus is inactive.
Публикации COVID-19
Science. 2020 May 6;eabc1932. DOI: 10.1126/science.abc1932.
Emma Risson. Inactivated Vaccine for SARS-CoV-2. Nat Rev Immunol. 2020 Apr 30;1. DOI: 10.1038/s41577-020-0334-1.
Клинические исследования
1.
Название протокола
A Randomized, Double-Blinded, Placebo-Controlled, Phase Ⅰ/Ⅱ Clinical Trial, to Evaluate the Safety and Immunogenicity of the SARS-CoV-2 Inactivated Vaccine in Healthy Adults Aged 18~59 Years
Дата начала и окончания КИ
April 16, 2020 - December 13, 2020
Название организации, проводящей КИ
Sinovac Research & Development Co.
Страны
China
Фаза
I-II
Кол-во пациентов
744