Пирфенидон (Pirfenidone)
Международное непатентованное наименование
Пирфенидон (Pirfenidone)
Торговое наименование
Esbriet
Производитель, страна
Roche Holding, Switzerland; Genentech, USA
Лекарственная форма
capsule, 267 mg
Механизм действия
Pirfenidone is an orally active small molecule drug that may inhibit collagen synthesis, down regulate production of multiple cytokines and block fibroblast proliferation and stimulation in response to cytokines. Pirfenidone has demonstrated activity in multiple fibrotic conditions, including those of the lung, kidney and liver. It is being investigated by InterMune.
Клинические исследования
1.
Название протокола
Prospective exploratory clinical research on the efficacy and safety of pirfenidone capsules in the treatment of severe novel coronavirus pneumonia (COVID-19)
Дата начала и окончания КИ
March 1, 2020 - December 31, 2020
Название организации, проводящей КИ
The third xiangya hospital of Central South University
Страны
China
Кол-во пациентов
40